Synonym(s): - AIMAH - Adrenocorticotropic hormone-independent macronodular adrenal hyperplasia - Corticotropin-independent macronodular adrenal hyperplasia
Classification (Orphanet): - Rare endocrine disease - Rare infertility Entire classification		Classification (ICD10): - Endocrine, nutritional and metabolic diseases - See
Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: any age Type of inheritance: autosomal dominant		External references: 1 OMIM reference - See No MeSH references
More Info - Orphanet

Gene symbol	UniProt reference	OMIM reference
ARMC5	Q96C12	615549

- Cortico-adrenal hyperplasia / hypersecretion
- Cushingoid morphotype
- Failure to thrive / difficulties for feeding in infancy / growth delay
- Round face
- Thin skin
- Truncal obesity

- Asthenia / fatigue / weakness
- Bruisability
- Chronic arterial hypertension
- Diabetes mellitus
- Hirsutism / hypertrichosis / Increased body hair
- Humour troubles / anxiety / depression / apathy / euphoria / irritability
- Metrorrhagia / menorrhagia / hemorrhagic cycles / hyper / poly / spanio / dysmenorrhea
- Muscle weakness / flaccidity
- Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets
- Urinary / renal lithiasis / kidney stones / nephritic colic

- Autosomal dominant inheritance
- Meningioma